"iTunes 12.1 (Mac)
This update introduces a new iTunes widget for Notification Center in OS X Yosemite. See what's playing, skip ahead, and even buy songs while listening to iTunes Radio - right from Notification Center. This update also improves performance when syncing with your iPhone, iPad, or iPod touch.

For more information, please see: https://support.apple.com/kb/HT6546.
(article is "Using the new iTunes", as of post time last revised Nov. 2014.)

File Size: OS X (216.6 MB) Windows (108.8 MB) Windows64 (152.4 MB)

Mac System Requirements
- OS X version 10.7.5 or later
- 400MB of available disk space
- iTunes in the Cloud, iTunes Match, and iTunes Radio availability may vary by country
- iTunes Radio requires OS X version 10.7 or later
- iTunes Extras requires OS X version 10.9.3 or later"

There's some user posts on iTunes 12.1 in Apple's iTunes forum.
  

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• OS X: Printer and scanner software available for download
  
  
• Manage content manually on your iPhone, iPad, and iPod
• If your iPhone, iPad, or iPod touch won't connect to a Wi-Fi network
• Use AirPlay to wirelessly stream content from your iPhone, iPad, or iPod touch

(Topic-based page of Tips, Troubleshooting & How-To articles for Mac/OS X/iOS Users.)
  

• Review of Grim Fandango Remastered (wired)
• iTunes 12.1 for Windows (64-bit - for older video cards) (Apple)
• Intel Launches New Site For All Things Wireless (intel blog)
• LG 5.09.02 update for 55EA8800 & 55EA9800 OLED TVs